We just recently had to reboot the entire server running SmarterMail and many of our clients started reporting SMTP errors when trying to send out email from Outlook, Entourage etc.... This is the following Outlook error message: Task 'mail.xxxxxx.xxx - Sending' reported error (0x80042109) : 'Outlook is unable to connect to your outgoing (SMTP) e-mail server. If you continue to receive this message, contact your server administrator or Internet service provider (ISP).' We are quite puzzled becuase all was working very well until we had to restart the server. We checked out the SMTP settings in our SmartMail and all looks to be the same as always. We require SMTP Authentifcation and our port settings in Outlook are set to 110 for Incoming and 8025 for Outgoing. Can anyone please help us figure out what the cause may be? Thanks!